Here, a large library of vascular network images was analyzed by the measure of each sample’s morphology and oxygen transport potential. Further, the commonly reported morphological metrics may not correlate to the network’s biological function-oxygen transport. While vascularization is emerging as a necessary physiological organ-level feature required in most such systems, there is no standard tool or morphological metric to measure the performance or biological function of vascularized networks within these models. Vascularized microphysiological systems and organoids are contemporary preclinical experimental platforms representing human tissue or organ function in health and disease.
0 Comments
Leave a Reply. |